Tottenham Hotspur take on Southampton in Premier League action on Sunday, with Mauricio Pochettino’s men starting an important run of fixtures that could define the club’s season.

While glamour ties against Manchester United, Liverpool, Arsenal and Juventus are all on the agenda for the next month, Spurs will firstly look to continue strong recent form and record three points on the south coast.

Tottenham first-teamers Toby Alderweireld, Harry Winks and Danny Rose remain sidelined and unavailable through injury, while Hugo Lloris could miss out against Southampton due to illness.

However, with Pochettino picking his side, it may well be time for a Spurs first-team regular from last season to be recalled into the starting XI.

Victor Wanyama has spent the majority of the campaign on the sidelines through injury but has recently returned to availability for Tottenham.

A handful of cameos from the bench have given the Kenya international a taste of Premier League action again but Pochettino has as yet resisted the urged to bring the African powerhouse back into the Spurs starting line-up.

While Eric Dier has continued in the Tottenham midfield of late, the clash with Southampton could well be the perfect opportunity to give Wanyama more of an outing and play him from the off.

The 26-year-old was an integral part of the Spurs side last season, with his energy, work-rate and ability to break up the opposition’s play key to the side’s success.

After a week’s training camp in Barcelona, Wanyama will be closing in on full fitness and Tottenham should unleash him against his former club Southampton.

While Dier’s versatility continues to be a real asset for Spurs, the Kenyan is a more-rounded option in the centre of the park.

With big games coming up, Tottenham supporters will hope to have first-choice midfield pairing Mousa Dembele and Wanyama fit and firing for crucial Premier League and Champions League clashes.